We break down the key differences between traditional cigarettes and e cigarettescovering: 1 Their compositions and ingredients. 2 The health risks associated with both. 3 Nicotine levels and addiction potential. 4 The impact Difference Between E Cigarette And Vape MOH needs to clarify differences between smoking and vaping E cigarettes: Not What It Seems Cape Girardeau County Public Health What is vaping? What are e cigarettes? Is it as harmless as it is made out to be? The truth is many e cigarettes contain nicotine, a highly addictive substance that can affect brain Vaping Information Substance Use Prevention Services Youth Services System, Inc. Youth Services System, Inc.